The computer-based non-linear analysis (NLS) as a dynamic non-invasive informative method is increasingly used to examine the status of health affected by pathologies of different origin. The NLS can be applied both in vivo ( to acquire an NLS-spectrum of one or another part of any organ or tissue) and in vitro ( to obtain an NLS-spectrum of extracts from tissues, biological fluids or cells); while, rather often both approaches can be combined for a more accurate data interpretation. The usage of NLS at a clinic requires devices production an at least 20-30 mT eddy magnetic field. The proceedings of the latest International Congress of Medical Doctors (200 and 2001), that dealt with new methods of diagnostics give evidence of of a growing number of NLS-investigations used for the diagnostics purposes - the 2000 summit heard 16 presentation ion the subject, while in 2001 there were twice as many.

    S.D. Tutin et.al. informed of the possibility to use the NLS to diagnose abscesses in the encephalon. It appears, that at an abscess in the encephalon in the NLS-spectrum, during the biochemical homeostasis evolution some signals from lactate and amino acid are detected, which disappearing the course of treatment. The NLS data in vivo correlated well with the result of abscess sample tests made by means of MRC with the high resolution in vitro.

    Using the NLS-method the dynamics of metabolic change in the encephalon when treating epilepsy can be traced. Some data are available, that indicate a possibility to register a decline in oxidative phosphorylation in the lower limbs muscles with constriction of the vessels caused by arteriosclerosis. In the course of treatment the muscles metabolism appears to improve. Another trend in the application of the NLS method is detection of metabolic disturbance of phosphoregic compounds at muscular atrophy related to pathology in the musculoskeletal system. some promising prospects for myocardial infraction diagnosis by means of the NLS method were describe by U.A.Shovkoplyas et. al., who studied the ATP exchange in the myocardium. At the myocardial infraction its level was proven to decrease.

    The NLS-analysis method was employed to study the dynamics of change in the metabolism of lipids in the liver affected by cirrhosis. The NLS-investigation of the pancreas affected by malignent degeneration allows diagnosing tumor progression, judge of the efficiency of radiation or chemotherapy and also adjusting individual dosage schemes for inoperable patients.

    Moreover, NLS is reported to be used to diagnose CNS disorder, cardiovascular discase, muscular system disorder, prostatic tumor, mammary gland tumors, and in addiction to monitor radiation - and medicinal US therapies. The researches have demonstrated the diagnostic importance of NLS for arteriosclerosis, apoplexy, encelophalomyclitis and vacuities. NLS allows estimating the phase of a pathology and activity of the nidus, determining a relationship between genetic characteristics, clinical symptoms and metabolic deviations in the encephalon. NLS helps to differentiate bengin and malignant tumors in the mammary gland. The studies of abnormal changes in the prostate gland by means of the NLS showed that the method allowed to identify an incipient change in the gland tissue and pick out the appropriate therapy in good time.

    So now the NLS devices(3D-NLS、Bioplasm-NLS and so on) with NLS method are widely applied in every walk of life.