Technological innovations of the recent years in equipment for non-linear diagnostics and software resulted in cardinal extension of NLS-research application area and improvement of images quality. One of the promising directions for the development of NLS-diagnostics with metatron 4025 hunter is a mode of multidimensional virtual reconstruction of an NLS-image, allowing to visualize crosscuts and anatomical reconstruction of a researched area, which remain invisible during application of two-dimensional scanning only. This method offers the possibility of data manipulating, using rotation and zooming, rendering true anatomy of organs in a direct projection. Three-dimensional NLS-scanning has a certain technical and practical advantages in visualization of anatomical and pathological structures in comparison with two-dimensional visualization. The method allows to make a crosscuts of acquired image, for example frontal ones, or to isolate separate areas in Fast Vision mode. It makes possible to see an internal structure of a parenchymatous organ, and if there are areas of affection inside the investigated region, an operator can isolate and zoom in areas of a parenchyma and thus see intratissual growths – in NLS-ultramicroscanning mode. Spectral-entropic analysis (SEA) mode allows to define morphological character of a researched area by comparison of spectral similarity with etalon processes.

    According to T. Guseva et al., three-dimensional NLS is better in investigation of anatomical motion of hepatic vessels and biliary ducts, than standard two-dimensional NLS-investigation.

    A. Schvack in his work evaluates practicability of three-dimensional NLS-scanning application in work with patients suffering from obstructive diseases of bile-excretory system. After comparison of three-dimensional NLS-scanning with endoscopic retrograde cholangiopancreatography it was noted that three-dimensional NLS-scanning has almost the same efficiency and informativity in evaluation of biliary system pathology as endoscopic retrograde cholangiopancreatography.