Application of high-frequency NLS-technologies with biophilia nls, providing visualization of vascular pattern, allows to detect with high degree of sensitivity (up to 100%) a number of reliable and indirect NLS-signs, accompanying laboratory manifestations of AP. We saw no dependence of these signs on sex and age of patients, etiological aspect, and the fact either it was a primary attack of AP or aggravation of a chronic process.

Identified as reliable NLS-graphic changes of renal structures and staging of their development are defined by dynamic morphological stereotype of AP, they completely associate with manifestations of the disease pathomorphogenesis. It allows to speak about NLS-semiotics of AP, assuming NLS-graphic stages of renal changes: infiltrative, purulent-exudative (pre-destructive), purulent-destructive (lysis of tissue) and reparation stage.

Results of the first NLS-study of a patient with assumption of AP, taking into consideration knowledge of NLS-semiotics, give a possibility to acquire necessary information about presence, stage, spreading of inflammatory process in a kidney; following monitoring of detected changes allows to judge about dynamics of the process – its development speed and spreading.