Timely and accurate diagnostics of pancreatic diseases, without which efficient treatment is not possible, is one of the main goals of a modern gastroenterology. It is determined by increasing of disease incidence and difficulties in a differential diagnostics due to absence of pathognomonic clinical symptoms, especially in the early stages of an illness. The difficult is differential diagnostics between pancreas head cancer and a chronic pseudo-tumor-like pancreatitis that sometimes result in complications requiring surgical interventions. These diseases may look like stomach and duodenum ulcer, pylorus stenosis and be accompanied by gastrointestinal hemmorhage and acute pain in superior parts of stomach. Chronic pancreatitis is diagnosed in 0.2-6.8% of adults. It is diagnosed in 6-8% of all digestive organs diseases. Examination of patients suffering from pancreas pathologies must ensure accurate diagnosing allowing to choose adequate tactics of treatment in proper time.

Choosing of diagnostic method depends on its availability, informativity, possibility of graphic registration of acquired data, safety and affordability. At the present moment neither method of clinical and hardware examination cannot solve problems of modern diagnostics of pancreas pathologies independently.

Leading position in detection of pancreas pathologies is taken by radiological methods, although their accuracy is far from perfect.

Recently appeared NLS-diagnostics method allows to acquire sufficiently accurate information about parenchyma’s and pancreatic ducts system’s condition. But until now two-dimensional NLS-graphy leaves unsolved certain issues related to spatial relations of examined structures and character of affection; in theory this issues may be addressed by three-dimensional NLS-graphy with spectralentropic analysis (SEA) of tissues.

So, one of the most prospective directions of NLS-diagnostics development is a method of three- dimensional reconstruction of NLS-image, allowing to visualize projections hidden for two-dimensional scanning and to carry out anatomical reconstruction of researched area. The 3D-NLS research by metatron hunter allows to see any projection of acquired image, select separate parts of it and operate the data interactively using rotation and scaling of researched structures.