Indications for NLS-graphy fulfillment are symptoms related to tumor development in nasopharynx, which may be divided into nasal, auricular and neurological depending on localization.

Shortness of nasal breathing happens at tumor localization in nasopharynx. Increasing shortness of nasal breathing is accompanied by mucopurulent and purulent discharge with blood admixtures from nasal cavity. Number of complains for shortness of nasal breathing depends on exophytic component of tumor that closes openings and on additional inflammations. If surface is ulcerated periodically appearing bleeding can be detected; it becomes dangerous at angiofibroma.

If tumor is localized at side wall in front of auditory tube orifice, Trotter’s symptom complex may be developed: hearing impairment at affected side of head, neuralgia and anaesthesia of trigeminal nerve third branch’s branchlet and unilateral limitation of soft palate mobility. If tumor is localized near auditory tube orifice leading positions are taken by hearing impairment, tinnitus aurium, stuffiness in ear.

Neurological symptoms appear if tumor spreads to surrounding tissues. Most frequently neurological disorders develop if tumor spreads into skull base, posterior and side walls of nasopharynx, at the same time symptoms of almost all pairs of cerebral nerves affection are detected: develops paralysis of abducent nerve, facial nerve, appear immobility of one half of larynx, aglutition, disorders of sensitiveness, taste and tongue declination.

Abovementioned disorders develop at continuous presence of tumor. At initial stage of nasopharynx tumor development symptoms of diseases are missing, and the first clinical presentation of NPC is appearance of enlarged lymph nodes at neck in 50% of cases. This fact evidences that NPC is characterized by early regional metastatic disease. Size of primary tumor does not correlate with presence of regional metastatic disease. Even at small and superficial invasions of primary tumor, one can detect multiple metastases both from affection side and crossed and bilateral ones, which often localized in deep group of jugular lymph nodes. Large-sized metastases cause pain sensation and Gorner’s symptom complex is developed, characterized by constriction of palpebral fissure, pupil and eyeball retraction.

Examination of nasopharynx was carried out with modern devices Bioplasm NLS.