The systems of nonlinear diagnostics (NLS) have acquired wide reputation recently. Even in those few cases where the clinical symptomatology is very typical the method of NLS-diagnostics brings some extra information about the size of damage and allows judging about the prognosis. In overwhelming majority of cases it has principal significance for diagnosing and consequently for the correct choice of cure.

In 2000 the Theory of quantum entropic logic created by academician Svyatoslav Pavlovitch Nesterov, which underlies the method itself, celebrated its 20th anniversary. So the nonlinear diagnostics is the youngest method among other hardware-based methods of diagnostics. However its discovery became a very important landmark in diagnostic medicine.

The apparatus for NLS-diagnostics (metatron) was created by Vladimir Igorevitch Nesterov, who offered in 1988 a trigger gauge and thus founded the idea of the apparatus.

Then Mr. Nesterov founded an Institute of Practical Psychophysics (IPP) and at once began active work on creating and improving NLS-diagnostics systems. The period from 1990 to 1995 was characterized by clinical tests of the first apparatuses. Late 90’s were marked by a rapid growth in commercial manufacture of apparatuses and a break-through in quality of the results obtained.

The NLS-method is still at its stage of development. The diagnostics methodologies are being improved so fast that the system versions are updated every six months. Due to introduction of new apparatuses with digital trigger gauges the NLS-diagnostics became not only faster but different in terms of quality. Obviously the dynamic methodologies such as the three-dimensional visualization of the examination results very soon will become routine practice. The methodology of vegetative testing is a striking example of their fast introduction. It is used so widely that one should speak sooner of a more strict specter of indications for it than of its popularization.

The Institute of Practical Psychophysics keeps searching for new methods of investigation based on NLS-systems. The results are very promising.

The NLS-analysis in contrast to NMR (Nuclear Magnetic Resonance) and computer tomography does not require high-density fields. The method looks prospective for research of metabolism in particular on cellular level.

The improvement of NLS-method follows not only the way of technical novelties but also the way of new applications. The simplest surgical manipulations such as biopsy for a long time are carried out under control of ultrasound, fluoroscopy and computer tomography. Now we have such an opportunity, and the biopsy became possible under control of NLS. However the attention of surgeons is attracted by more complicated operations carried out using this methodology.

The cost of equipment（such as Biophilia Tracker, Meta Hunter） for NLS-diagnostics remains extremely low as compared to other hardware methods. This must promote wide spreading of this method in the countries with low level of income of their population. Among all methods of hardware diagnostics the NLS gives the picture, which is to the greatest extent close to the pathologoanatomic one. This condition along with its harmlessness stimulates rapid development of NLS-diagnostics method.