Three-dimensional NLS-research by metatron 4025 hunter with the application of spectral-entropy analysis, carried out during surgical oncotomy, allowed us to detect additional tumoral neoplasms, not registered by two-dimensional NLS research in 37% of the patients. Application of three-dimensional methods makes it possible to specify the extent of tumor local spreading process; control the depth of urinary bladder wall resection; and decrease the risks of developing complications during the oncotomy.

    Usually, the diagnostics and morphological verification of rectal cancer does not present difficulties. However, evaluating the organ wall’s degree of invasion is not always possible using standard diagnostic methods. Traditional two-dimensional NLS-research is already widely used as a diagnostics method of recurrent rectal cancer after organ extirpation. Nevertheless, primary diagnostics of the disease using two-dimensional NLS-graphy is hindered due to several reasons; first and foremost, given that in two-dimensional NLS-scanning the rectum is visualized only partially (80% of the whole organ surface area).

    Application of three-dimensional NLS-graphy makes it possible to accurately differentiate between all layers of rectum walls, and thus to diagnose the depth of tumor infiltration and identify the stage of the disease, using spectral-entropy analysis. This method helps detect changed lymph nodes over 1.5mm in size in pararectal lymph node metastatic disease. During the monitoring of pre-operational radiotherapy, three-dimensional NLS-graphy helps detect accurately the decrease in tumor size; identify changes in their structure, related to medical pathomorphism; and identify the decrease in pararectal tissue tumoral infiltration. Therefore, three-dimensional NLS-graphy may be considered as a method of rectal cancer primary diagnostics. It allows physicians to resolve the most important diagnostic issues, related to identifying tumoral process length, the extent of the tumor’s local spreading and monitoring pre-operative treatment efficiency. In organ preserving operations, three-dimensional NLS-graphy may be used as an efficient method of recurrent tumors early diagnostics in the anastomosis area.