Diagnostics and treatment of malignant neoplasms are the most urgent issues in modern medicine. Oncologists face not only problems of primary and updating diagnostics of tumoral diseases, but also evaluation of various methods of tumor treatment efficiency and well-timed diagnosis of recurrent tumors after treatment procedures. The introduction of new three-dimensional technologies of NLS-pictures acquiring into clinical practice allows the solving of the abovementioned diagnostic problems at a qualitatively new and higher level.

    Application of three-dimensional visualization of organs and tissues significantly extended the potential of NLS-diagnostics. Today we may speak of truly early diagnostics of tumoral diseases at the first, pre-clinical stage of patient examination. Three-dimensional NLS examination allows not only to reveal minimal structural changes in organs and tissues, but precise evaluation of tumoral process spreading extent. Further, when combined with the use of spectral-entropy analysis, it makes possible to identify disease stage and choose the adequate method of patient treatment.

    In group of malignant tumors of liver, metastatic invasion holds leading positions. It is well-known that the most frequent reasons for liver metastatic disease are malignant tumors of the large intestine, rectum, stomach, pancreas, mammary glands and lungs. At metastatic disease, the shape, structure, size of parenchyma and vascular pattern of the liver are more or less changed, depending on tumor existence duration, as well as number and size of tumoral nodes. In addition to three-dimensional NLS-graphy by metatron 4025 hunter, diverse variants of dopplerography (initially energy color mapping) may be used to solve the problem of differential diagnostics of benign and malignant changes in the liver parenchyma. Three-dimensional NLS-graphy method allows the visualization of a three-dimensional picture of vessel location and form, marking them by a certain color in the background of the organ’s normal picture. In this aspect, the method is rather close to x-ray angiography and allows to accurately visualize large and minute vessels.