Intrahepatic cholangiocarcinoma is diagnosed in 7-35% of all malignant hepatic neoplasms cases. Early detection of this pathology is one of the most difficult tasks in diagnostics in hepatology, because the tumor often develops against the background of chronic diseases of liver and bile-excretory ducts and disguised by symptoms of these diseases.

    In recent years periodicity of cholangiocarcinoma detection increased. It is explained by introduction of modern methods of visualization, which allow to specify localization and prevalence of tumorous process more accurately. The high point of disease incidence is at the age of 50-70. The incidence of the disease in men and women is almost equal.

    Methods of the highest importance for primary diagnostics of bile-excretory dusts pathologies are non-invasive methods of research (ultrasound scanning, computed tomography and magnetic resonance imaging). But these methods cannot clearly detect a localization of a focal process and its character. Basing of acquired data therapists decide about the more accurate method of invasive diagnostics: endoscopic retrograde cholangiopancreatography (ERCPG), percutaneous transhepatic cholangiography (PTCG), and in some cases - angiographic study and liver biopsy. Choosing of a method is determined by its availability, information value, safety and affordability.

    Recently appeared method of non-linear diagnostics (NLS) by metatron 4025 hunter may now become the most available method for primary diagnostics of abdominal cavity diseases. One of the most-prospective trends of NLS diagnostics is three-dimensional NLS-graphy, which has certain technical and practical advantages in visualization of anatomic and pathological structures over other methods of hardware visualization. Data acquired after computer processing can manipulated, a plane of three-dimensional model cross-cut can be adjusted, thus allowing to investigate organs images in various projections. The objective of the present study is to evaluate possibilities of three-dimensional NLS-study in diagnostics of cholangiocarcinoma.